Abstract

Coloration of hypnotics of the barbituric acid series, such as Veronal, Luminal, Prominal, Dial, Amytal, Cyclopan, and Adorm, by condensation with various aldehydes was examined as a means of their identification. The possibilty of a formation of complex salts with Co, Ni, Mn, Fe, Al, Cu, Zn and Mg, was also examined and it was found that the coloration occured only with Co and Cu. The complex salts of Prominal and Cyclopan, which have N-CH3 group, with Co were found to be unstable that gave an example of a steric hindrance.

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