Abstract
Following 4 kinds of α-amino acids possessing benzimidazole nucleus were prepared by the use of acetaminomalonic ester and acetaminocyanoacetic ester, as those compounds were expected to possess antagonistic action against tryptophane, purine and vitamin B12: β-(Benzimidazole-2)-alanine, β-methyl-β-(benzimidazole-2)-alanine, β-(5-methylbenzimidazole-2)-alanine and β-methyl-β-(5-methylbenzimidazole-2)-alanine. The first two were able to inhibit the growth of Leuconostoc mesentroides, and the last two, E. coli.
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