Введение фармакофорных групп в бис(индол-1-ил) малеимиды и 6H-пирроло[3,4:2,3][1,4]диазепиноиндоло-[6,7,1-hi]8,10(7H,9H)-дионов

Abstract

The synthesis of bis(indol-1-yl)maleimides and polycondenced diazepines[1,4], which contain various functional groups and are the analogs of biologically active indolo[2,3-а]carbazoles, is described. Functional groups were introduced directly into diazepine and bis-indolylmaleimide molecules via eletrophilic substitution reactions using precursors containing such functional groups.