Abstract

Concerning the decomposition of a novel semisynthetic penicillin, aspoxicillin (ASPC) in aqueous solution, several labile products were isolated and their structures elucidated. The stepwise rearrangements of the penam ring were recognized and they were similar to the known decomposition system about the practical penicillins, in spite of the unique 6-acyl side chain of ASPC.

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