Abstract
Due to metabolic disorders in diabetes mellitus type 1 (DM1T) is a structural lesion of the central nervous system, that clinically manifested by cognitive dysfunction. The aim of the study was to evaluate the pattern of the brain in patients with DM1T by magnetic resonance imaging (MRI) in conjunction with the clinical, metabolic and cognitive impairment. The study involved 58 patients with type 1 diabetes aged 16-30 years, the control group consisted of 29 healthy young adults, matched by sex and age. Screening for cognitive impairment scale used Montreal (MoCa test). To analyze the structural changes in the central nervous system was performed on brain MRI device Siemens Magnetom 1,0 T. The study showed signs of atrophy of gray matter, the expansion spaces Virchow - Robin, white matter lesions of the brain correlated with the presence of chronic hyperglycemia, cognitive impairment, microvascular complications.
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