Повышение эффективности лечения синдрома сухого глаза у пациентов с синдромом Шегрена путем применения препарата бесконсервантных капель, содержащих гиалуронат натрия 0,4 %

Abstract

Purpose. To increase the effectiveness of the treatment of dry eye syndrome in patients with Sjogren’s syndrome by using the drug without preservative drops containing sodium hyaluronate 0.4%. Materials and methods. The research was carried out on the basis of “The Filatov Institute of Eye Diseases and Tissue Therapy of The National Academy of Medical Sciences of Ukraine”. The study included 14 patients aged 34 to 59 years (28 eyes) with dry eye syndrome concomitant with Sjogren’s syndrome. The examination of patients included: assessment of complaints, visometry, refractometry, culture tank from the conjunctiva, biomicroscopy, ophthalmoscopy, Schirmer’s test and Norn’s test, assessment of the “comfort of using drops” according to the questionnaire developed for this study. Results. Before the appointment of instillations, Norn’s test was 6.5 seconds (SD 1.56) with a minimum of 3 seconds and a maximum of 9 seconds, a median of 6.5 seconds. After a month of treatment while taking drops, Norn’s test in the first group averaged 14.86 (SD 1.07) versus 13.86 (SD 1.07), but the difference was not statistically significant (p=1.0). The average number of instillations required per day for the first group was 4.14 (SD 1.06) and for the second group it was: 5.29 (SD 1.11). Conclusion. Instillations of non-preservative drops containing sodium hyaluronate 0.4% (in a bottle equipped with an innovative reusable push-type ophthalmic dispenser (OSD) in the treatment of dry eye syndrome in patients with Sjogren’s syndrome are quite effective and very convenient to use.