活性酸素を介した生殖戦略：子宮と卵巣における活性酸素とその消去酵素の役割

Abstract

For successful pregnancy, progesterone production by the corpus luteum and decidualization of the endometrium are necessary. In contrast, regression of the corpus luteum and endometrial shedding should be induced promptly for the next conception when pregnancy does not occur. Superoxide radical and its scavenger, superoxide dismutase (SOD), play important roles in the regulation of cellular function. The present review focuses on the roles of superoxide radicals and SOD in the regulation of corpus luteum function and endometrial function.