Abstract
In experiments on rats, influence of preventive administration of sulfur containing radioprotectors (cystamine, gammaphos), agonists of α 2 adrenoreceptors (indraline, naphthyzin) and immunomodulators (prodigiosane, betaleukine) on reparative processes in local (due β or X-ray irradiation) and combined radiation injures (general irradiation with superficial or deep radiation skin burns) is investigated. It is established that aminothiols and adrenomimetics show their radioprotective efficiency only in superficial radiation burns, with the most expressed wound healing action for cystamine. In combined radiation injures including superficial skin burns, reparative processes are accelerated when using cystamine, naphthyzin and betaleukine; in injures combined with deep radiation burns – when using cystamine or betaleukine.
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