Abstract

TA-058, a new penicillin derivative, was administered to 21 patients with otorhinolaryngological infections.1. It was effective in all eight patients with tonsillitis, in six of nine patients with acute exacerbation of chronic otitis media and in the other cases.2. The bacteriological efficacy rate was 85.7% (18/21).3. TA-058 was moderately or markedly effective in all four patients who had not responded to previous medications.4. Drug eruption was observed in one of the 21 patients treated with TA-058.5. TA-058 is very useful antibiotic agent for patients with otorhinolaryngologic infections.

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