Abstract
Rheological characteristics of an original pharmaceutical composition of nanostructured (ultradisperse) silver system stabilized by arabinogalactan have been studied by the dynamic rheology method in comparison to the officinal silver-containing preparation dermazin. Significant differences in rheological characteristics of the two soft medicinal forms have been revealed, which are relevant to their fixation on skin surface, bioavailability of active ingredients, and production technology. It is established that the original pharmaceutical composition of ultradisperse silver system stabilized by arabinogalactan is a structured liquid with pronounced non-Newtonian flow nature, possessing viscoplastic and thixotropic properties. The rheological parameters of the proposed composition correspond to the technological requirements of rheological optimum for extrusion of hydrophilic gels.
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