Профілактика невдалих спроб застосування допоміжних репродуктивних технологій

Abstract

The objective: depression of frequency of unsuccessful attempts of auxiliary genesial technologies on the basis of studying of new aspects of pathogenesis of female sterility, and also improvement and introduction of algorithm of prognostic and treatment-and-prophylactic actions. Patients and methods. Аt 1 stage (forecasting of results of ART) 97 married couples (1 group) which passed sterility treatment were surveyed. At the 2nd stage (prophylaxis of unsuccessful attempts of ART) 108 patients of genesial age who had in the anamnesis of 2 and more attempts of ART were surveyed. Results. Unsuccessful attempts ART arise at various reasons of sterility: a tubal and peritoneal factor – 48.5%; endocrine disturbances – 44.3%; a man’s factor – 29.9%; an external genital endometriosis of the I–II st – 21,7%, and also a combination of above-mentioned reasons of sterility – 60.8%. At female factors of sterility depression of an ovarialny reserve and unavailability of functional state an endometrium which take place are the main reasons of unsuccessful attempts of auxiliary genesial technologies as is independent, and in a combination. Conclusion. For rising of efficiency of ART it is necessary to use, first of all, effective forecasting taking into account functional, laboratory and morphological methods of researches. Further, it is necessary to develop the individual program of specific preparation taking into account all preliminary results. Key words: auxiliary genesial technologies, unsuccessful attempts, prophylaxis.