Альтернатива гормональным и нестероидным противовоспалительным средствам в лечении вторичной дисменореи, обусловленной аденомиозом

Abstract

Secondary dysmenorrhea or painful menstruation are observed in almost half of young women and significantly affect the quality of life, primarily in the emotional, psychic and communication spheres, and also often cause the loss of temporary work capacity. Secondary (organic) dysmenorrhea is caused by various pathological diseases in the pelvic organs (uterine leiomyoma, ovarian tumors, pelvic inflammatory processes, malformation of the genital organs, adhesive process in the small pelvis, etc.) and in particular adenomyosis (internal endometriosis). This disease, leads to disruption of reproductive function and disability, causes feelings of inferiority, causing physical and moral harm to women aged 20–40 years. According to different data, the incidence of endometriosis in populations varies from 7 to 65%. In a significant number of cases, conservative (hormonal) therapy of endometriosis does not reach its goal and has many negative effects on the woman’s body. In this regard, the search for safer and more effective treatment is an extremely urgent task. The use of drugs of natural origin regulating the blood supply, tropism, metabolism and functional state of the reproductive endocrine system in the treatment of secondary dysmenorrhea finds a more favorable ground for compliance and is increasingly prevalent. The advantage of such drugs is low toxicity and the possibility of prolonged use without the risk of serious adverse reactions. Positive changes in the hormonal status and a good clinical effect with the use of drugs of natural origin in patients with secondary dysmenorrhea associated with adenomyosis, confirm the advisability of its use in the pathogenetic treatment of this pathology. Key words: secondary dysmenorrhea, endometriosis, adenomyosis, nonsteroidal anti-inflammatory drugs, adverse reactions, combined oral contraceptives, multi-component non-hormonal drug.