Стан піхвового біоценозу у жінок з проблемою генітального пролапсу

Abstract

The objective: to identify clinical and diagnostic features of vaginal biocenosis in women with genital prolapse (GP) and the need for its correction. Materials and methods. The study involved 120 patients with GP of grade 1-2 who were divided into two groups. The treatment group (Group 1) consisted of 90 patients who were divided into three subgroups: 1a (n=30) with GP correction by platelet-rich autoplasma, 1b (n=30) with GP treatment by hyaluronic acid-based agent, 1c (n=30) with GP treatment using laser system CO2 (SmartXideDOT, DEKA, Italy). The experimental group (Group 2) consisted of 30 patients who underwent GP correction by training the pelvic floor muscles individually according to the standard method. Results. The violations of the vaginal biocenosis were revealed in both study groups at the initial stages of GP formation. They were mostly due to the atrophic changes of the vaginal mucosa and in the form of bacterial vaginosis diagnosed according to Nugent’s criteria. At the initial stages of GP formation, there was registered an increase in the duration of vaginal biocenosis disorders in patients with GP on the background of urogenital disorders, which may be associated with concomitant somatic diseases, indicating the need to correct the biocenosis as an important component in the correction of initial forms of GP. Conclusion. Thus, timely conservative treatment of GP will not only correct GP, but also improve the state of the vaginal biocenosis, which significantly affects the quality of life of women with genital prolapse. Keywords: genital prolapse, vaginal microflora, vaginal atrophy, autoplasma, hyaluronic acid, CО2-laser.