Однофотонная эмиссионная компьютерная томография с коррекцией аттенюации в верификации нарушений микроциркуляции миокарда у пациентов с болевым синдромом в грудной клетке и интактными коронарными артериями

Abstract

The paper estimated the role of the attenuation correction (AC) for single-photon emission computed tomography combined with computed tomography (SPECT/CT) in the assessment of myocardial perfusion in patients with chest pain and unaffected coronary artery. The study included 31 patients, each of whom had a selective coronary angiography and rest/stress SPECT/CT of the myocardium made with 99mTc -MIBI with- and without CA. Stress-induced myocardial ischemia of varying incidence and severity was detected in all patients according to scintigramm without and with AC on SPECT. However, the perfusion parameters showed the prevalence and severity of stress-induced perfusion deficit which were significantly lower after the correction. The average values of quantitative parameters of perfusion scintigramm on rest were also lower with CA, although not significantly different when compared without CA. Quantitative parameters of myocardial perfusion to assess the functional state of the myocardium by SPECT/CT with attenuation correction are of great diagnostic value.