Характеристика лекарственной чувствительностимикобактерий туберкулеза, выделенных от впервые выявленных больных туберкулезом, сочетанным с ВИЧ-инфекцией

Abstract

The paper characterizes drug susceptibility in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection. The investigators have studied the spectrum of drug resistance in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with and without HIV infection (172 and 309 clinical isolates, respectively). There are differences in the rate of primary drug resistance to antituberculosis drugs in patients with and without HIV infection (59 and 43.5% of the cases, respectively). The HIV-infected have also shown high rifampicin resistance rates in Mycobacterium tuberculosis (41.7%). The reasons for these differences are as yet unknown and call for further investigation.