Abstract
Features of production of primary and secondary active forms of oxygen (AFO) by neutrophilic granulocytes of patients with stomach cancer (SC) were studied. During the period to surgical treatment parameters of luminol-dependent and lyutsiginin-dependent chemiluminescence (CL) are decreased relative to reference quantity. For first 24 hours after surgical operation activation of oxygen producing system of neutrophils connected with a stage of primary AFO formation is observed, at the same time, insufficiency of the biochemical reactions cascade providing secondary AFO formation remains. Neutrophils of patients blood with SC for the 7th days after surgical treatment are characterized by stabilization of the mechanisms regulating a basic level of AFO production, however the evident activation of the metabolic reactions directed on production of secondary AFO at stimulation of cages by opsonized zymosan is observed.
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