滋賀県における高コレステロール血症とコレステロール, 脂肪酸摂取量の解析

Abstract

Serum cholesterol levels in 31, 237 males and 78, 191 females were measured in order to estimate the prevalence of hypercholesterolemia (serum cholesterol; higher than 240mg/dl) in 9 districts of the Shiga prefecture. The daily cholesterol and fat intakes (polyunsaturated and saturated fatty acids) of 11, 375 Shiga residents were also analyzed in order to study the relationships between hypercholesterolemia and food intake.The prevalence of hypercholesterolemia in urban and rural Shiga was 9.2% (corrected value by population pyramid in Japan: 10.0%), 5.8% (6.3%) in males and 18.6% (10.2%), 12.4% (7.3%) in females. The prevalence of hypercholesterolemia in the Shiga prefecture—male 14.9% (8.5%), female 6.9% (7.6%)—was approximately equal to the Japanese average. However, the prevalence of hypercholesterolemia among females in urban Shiga was even higher than among females in metropolitan Japan. Among 50% of aged urban female residents, the prevalence of hypercholesterolemia was higher than 220mg/dl; among 25% of these residents, it was higher than 240mg/dl.The daily intake of cholesterol (387mg) and fat (57.0g) by Shiga residents was similar to the Japanese average. But the daily intake of animal fat was higher, and the P/S ratio (polyunsaturated to saturated fat ratio) was lower in Shiga than the Japanese average. Cholesterol, fat and animal fat intake was highest in the highest prevalence area of hypercholesterolemia (the Ohtsu area) and lowest in the two lowest prevalence areas.These results suggest that hypercholesterolemia is quite high among aged urban females in the Shiga prefecture and support many previous reports that the high intake of cholesterol, fat and animal fat is related to a high prevalence of hypercholesterolemia.