Abstract

The study was carried out in 192 patients aged 18–25 years who underwent orthodontic treatment of dental-maxillary anomalies. We singled out 3 groups of patients who, after the orthodontic appliances being put on, were implemented various preventive measures against the inflammatory process. In the period before treatment, after 7 days, after 1, 3 and 12 months in the mixed saliva, the activity of lysozyme, the level of secretory immunoglobulin A and interleukins were determined. Measurements were performed with a vertical spectrophotometer Multiscan MCC 340. In all groups of patients, there was a gradual increase in the indicators of lysozyme activity, the level of secretory immunoglobulin A and interleukins; so by 3 months and by 1 year they came to their initial values. Rapid normalization of these indicators was noted in the third group of patients, where a full range of preventive measures was carried out using professional hygiene, antibacterial and immune therapy. The use of the appliances for orthodontic treatment is accompanied by the inflammatory process. The combined use of oral hygiene, antibacterial and immune therapy is most indicated in the prevention of the inflammatory process in the treatment of dental-maxillary anomalies.

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