Abstract

Immunotropic drugs are medications that affect the immune system (cells, synthesis of immunoglobulins, cytokines). Bacterial lysates (BL) appeared in 1970, as bacterial vaccines, but they do not cause resistant protective immunity formation. They stimulate specific IgA synthesis, activate dendritic cells, T-cells, cytokines synthesis, cause a shift in the balance towards adaptive immunity. Activation of local immunity reduces contamination of mucous membranes of the bacterial flora. Clinical effects associated with reduced ARI frequency and need for antibiotic treatment. A variety of immune preparations raises the problem of determining indications for medicines and knowledge of their action mechanisms. BL are commonly used in pediatrics, and they proved themselves as a safe medication that interacts with immune system cells, reduce frequency and severity of respiratory infections, need for antibiotic treatment.

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