Abstract

The main etiologic factor of periodontitis is the dental biofilm in the periodontal pockets. Biofilm is formed by the glycocalyx structure. Recently, the fundamental studies of photodynamic therapy (PDT) which used laser devices and photosensitizers to periodontal treatment have been reported. The advantage of PDT is that it can only affect the target tissue by combination of laser light with a specific wavelength to activate a photosensitizer and this photosensitizer does not have any toxicity. Therefore, the heat effect from laser device to other tissues becomes weak. Additional, it may be possible to destroy biofilm in the pocket where the laser fiber can not reach and evade side effects such as antibiotic. In this paper, the various clinical studies of photodynamic therapy (PDT) which have been reported until now and our studies are introduced. The possibility of application to periodontal treatment of PDT is also discussed.

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