Հակամանրէային դեղերի նկատմամբ մանրէային կուլտուրաների զգայունության որոշումը և կայունության մեխանիզմների ուսումնասիրությունը միզուղիների վարակների դեպքում

Abstract

The uncontrolled and irrational use of antimicrobial drugs in hospitals and outpatient settings (including at home) has led to the emergence of resistance mechanisms of bacterial strains. The increase in fluoroquinolone resistance rates in the 2020-2021 study proves the widespread use of antibiotics (in this case, fluoroquinolones) to treat secondary infections of bacterial origin or to prevent their occurrence during the COVID-19 pandemic. Based on the analysis of the data obtained, the use of fluoroquinolones, cephalosporins of III and IV generations, aminoglycosides of II generation for empirical treatment of urinary tract infections without bacteriological study and the results of sensitivity determination to antimicrobial drugs cannot be justified. Targeted and optimized use of antibiotics, as well as quality laboratory diagnosis and active infection control measures, can prevent the emergence and spread of drugresistant bacteria. The results of the study can be used in healthcare facilities to monitor bacterial resistance, to determine infection control strategies, and to develop policies for their use. Control and monitoring of resistant strains through detection of antibiotic resistance mechanisms, as well as extended analysis (according to the data from healthcare facilities, from regions, according to microbial species and stability mechanisms) requires continued research and long-term studies.