Abstract

Serum lipids and apolipoproteins were studied in 7 male patients with coronary artery disease (5 old myocardial infarction, 2 stable angina pectoris) and 4 control men undergoing a mild training program using aerobic threshold as a exercise intensity for 10 weeks. The training caused a significant increase in HDL-cholesterol (HDL-C) apo A-I and LCAT activity in control men. On the contrary, no significant changes in serum lipids, HDL-C and apolipoproteins were observed in patients with coronary artery disease. In one patient significant increase in HDL2-C level was observed by long term training (60 weeks), whereas no changes in total HDL-C level. There was a significant correlation between HDL-C level before training and increase in HDL-C level after training.The present suggest that mild exercise program in patients with coronary artery disease require more prolonged training period to obtain beneficial effects on lipoprotein and apolipoprotein levels.

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