Abstract
Recent advances of tho research on the age-related alterations of cellular and molecular defense systems have been reviewed with special emphasis on its relationship to reticuloendothelial system.Rapid progress of the research on the cytokine network and cellular interaction of defense systems began to clarify the precise mechanism of immunosenescence and to provide directions for therapeutic means in geriatrics.The proportion of the elderly in the world is rapidly increasing and so is the urgent need to provide sophisticated health care for the elderly.We must further intensify the research to strengthen the defense systems of the elderly, leading to provide measures for the longevity and quality of life of the elderly.
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