Abstract
A new method for the granulation of lipophilic substances is described using examples of an extract from the crust of Pygeum africanum (Hook. F. Kalkman) and polyextracts from Urtica dioica L. The proposed method is based on a combined process of melting and dispersion in aqueous solutions of surfactants, followed by the use of obtained dispersed solution as a binding agent for granulation. This technology is recommended for the production of solid dosage forms of drugs containing lipophilic substances.
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