Особенности терапии хронической гонококковой инфекции в ассоциированных состояниях у женщин при заболеваниях органов малого таза

Abstract

The purpose of research is to study in practice recurrent inflammation of the pelvic organs in women as the mainly cause of massive adhesion process and as a result to infertility. The current course of chronic gonococcal infection in women is asymptomatic without clinical manifestations. During 2009-2013 observation, examination and treatment 198 women were carried out. Women had a history of previous inflammatory diseases of the small pelvis, the diplococcic was revealed to these women during examination. Earlier repeatedly postponed inflammatory diseases of the small pelvis were in history of the women, as well as the patients after laparoscopic operations for infertility. All women previously had regular courses of conservative anti-inflammatory therapy. tively, they didn´t care for nothing. Periodically during preventive examinations or after scheduled examinations gynecologist, the increased number of leukocytes was noted in smears on the flora, in smears on oncocytology – the cytogram of inflammation. Neisseria gonorrhoea was revealed in most cases using the scraping of the three points by PCR. Neisseria gonorrhoeae has been combined : Escherichia coli (massive or modest growth), Trichomonas vaginalis, Enterococcus faecalis (massive or modest growth), U. Urealyticum (or M. Genitalium), Staphylococcus aureus (massive or moderate growth). The prescription of the Metronidazole in the dose of 0,5 mg 3 times per day (every 8 hours) for 2-3 days prior to the appointment of antibacterial drugs has brought the best result. Selection of antibiotics was reduced antibiotic therapy 3-4-5 generations: penicillins, cephalosporins ,carbapenems and monobactams, having (according to bacteriological examination) increased sensitivity to these strains of microorganisms. Conclusions: The patients with recurrent chronic inflammatory diseases of the pelvic organs in women scraping three-point PCR method shows better results identify Neisseria gonorrhoeae. Appointment of metronidazole by 0,5 mg 3 times a day (every 8 hours) for 2-3 days prior to the appointment of antibacterial drugs has brought the best result. Selection of antibiotics was reduced to β- lactam antibiotics 3-4-5 generations: penicillins, cephalosporins, carbapenems and monobactams, having (according to bacteriological examination) increased sensitivity to these strains microorganisms .