Abstract
The content of trace elements (manganese (Mn), iron (Fe), chromium (Cr), molybdenum (Mo), zinc (Zn), copper (Cu) in peripheral blood, and synovial fluid in 26 patients with osteoarthritis was studied. A decrease in the concentration of Mn (p = 0,02) and Fe (p = 0,02) and a decrease in Zn (p = 0,01) in the peripheral blood and an increase in the concentration of Fe (p = 0,01) and Zn (p = 0,02) in the synovial fluid in patients with osteoarthritis when compared with the control group. A statistically significant increase in the concentration of Mn (p = 0,001), Cr (p = 0,01), Zn (p = 0,002) and Fe (р<0,05) in the peripheral blood and a decrease in the concentration of Fe (p = 0,001) and Mn (p = 0,001) in synovial fluid in patients with gonarthrosis compared with patients with coxarthrosis Analysis of the trace element composition of synovial fluid and peripheral blood can be used in the complex diagnosis of patients with osteoarthritis.
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