Abstract

Investigation of indices and markers of periodontal, glossal and immune statuses and its possible dependence on age is subject of interest especially regarding high alcohol consumption rate in Russia and significant need for dental care in ethanol abusers. The aim of the study was to research periodontal, glossal and immune statuses of men with alcohol use disorder (AUD) depending on the age. Dental examination of indices of periodontal, glossal and immune statuses was carried out among two age groups of patients with second stage of AUD aged 25-44 years – «younger» and 45-64 years – «older». Methods of statistical analysis were Pearson's chi-squared test, Mann–Whitney U test and logistic regression. In the present study hygienic level of both groups was satisfactory (р = 0,210), intensity of inflammation in periodontal tissues was moderate (p < 0,001). According to CPI results, sextants with bleeding (35,1%) and calculus (23,4%)prevailed in younger age group, but in older age group shallow pockets (25,7%) and excluded sextants were more often (41,0%). We revealed significant differences between the groups within all codes (p < 0,001).The tongue dorsal surface test demonstrated predominance of code 1 (58,4% and 65,1%, respectively in younger and alder age group, (р = 0,422)) and code 2 (27,3% and 25,4% respectively, (р = 0,802). Statistically significant differences were obtained by the level of IgG (p = 0,004), IL-8 (p = 0,039) and cortisol (p = 0,028). Results of the present study have shown that patients with AUD have certain deviations compared to norm within the periodontal, glossal and immune statuses. Among older participants severe periodontal diseases according to higher PMA and worse CPI and increased IL-8 and IgG prevailed.

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