Возможности терапии эзофагопротектором в ведении больного ГЭРБ с внепищеводными проявлениями

Abstract

Gastroesophageal reflux disease (GERD) is one of the most common reasons for referral to a physician. Gastroesophageal reflux-associated extraesophageal symptoms occur in every third patient with GERD. Diagnostic difficulties and the prescription of effective treatment to rapid resolve GERD extraesophageal symptoms are still important issues when managing these patients. This paper summarizes data on the prevalence and pattern of GERD extraesophageal symptoms, as well as the efficacy and safety of therapies for GERD with extraesophageal symptoms with esophageal protector. The esophageal protector mechanically protects the laryngeal and esophageal mucosa, improving the recovery of its molecular cellular structure and normalizing barrier function, and reduces extraesophageal symptoms of GERD. The action of the esophageal protector is realized via its ability to envelop and protect the oropharynx and esophagus from the harmful effects of acid or biliary reflux, hydrate mucosa, and provide direct healing action. This results in a more rapid and complete recovery of the esophageal and laryngeal epithelium. KEYWORDS: gastroesophageal reflux disease, extraesophageal symptoms, laryngopharyngeal reflux, esophageal protector, hyaluronic acid, chondroitin sulfate. FOR CITATION: Lapteva I.V., Fedorin M.M., Nesterova K.I. et al. Therapy with esophageal protector in the management of GERD with extraesophageal symptoms. Russian Medical Inquiry. 2022;6(5):237–243 (in Russ.). DOI: 10.32364/2587-6821-2022-6-5-237-243