ИССЛЕДОВАНИЕ РЕМИНЕРАЛИЗАЦИИ ТВЕРДЫХ ТКАНЕЙ ЗУБОВ У ПАЦИЕНТОВ ПОСЛЕ ЛУЧЕВОЙ ТЕРАПИИ ПО ПОВОДУ НОВООБРАЗОВАНИЙ ЧЕЛЮСТНО-ЛИЦЕВОЙ ОБЛАСТИ МЕТОДОМ РАМАН-ФЛЮОРЕСЦЕНЦИИ

Abstract

Subject. Mineralization of hard dental tissues and its correction in patients after radiation therapy for malignant neoplasms.
 Objectives. To develop a method for remineralization of hard dental tissues in patients after radiation therapy for neoplasms of the maxillofacial area using Raman fluorescence spectroscopy.
 Methodology. The study was conducted on a group of people who had previously received radiation therapy for malignant neoplasms of the head and neck, matched by gender and age, who voluntarily agreed to take part in it. The main group consisted of 20 people who underwent the proposed remineralization complex. Comparison group – without using the proposed complex. A study of Raman fluorescence of teeth was carried out using the InSpectrum computer in three areas (neck, equator, incisal edge) in patients before and after correction.
 Results. Raman fluorescence diagnostics of the tooth surface made it possible to clearly see the difference in mineralization in digitized indicators. The data for patients in the main group after correction of mineralization (y = 304, x = 963 cm-1) are higher than for patients in the comparison group (y = 287, x = 963 cm-1).
 Conclusion. In different areas of the tooth surface, the level of mineralization of hard tissues differs: neck (216 ± 0.019, x = 963 cm-1), equator (389 ± 0.024, x = 963 cm-1), cutting edge (282 ± 0.016, x = 963 cm-1). The Raman fluorescence diagnostic method allows you to monitor changes in mineralization. 
 The developed method of remineralization of hard dental tissues in patients after radiation therapy for neoplasms of the maxillofacial area using Raman fluorescence spectroscopy makes it possible to influence mineralization and is recommended for further research to prevent the development of radiation caries