Загальні принципи і рекомендації з визначення пухлинних маркерів у клінічній практиці гінеколога

Abstract

Tumor markers play a large role in all aspects of cancer surveillance, from screening to follow-up after treatment, and their prudent use in clinical practice requires a thorough understanding of the basics of pathophysiology, methods of identification or testing, and their role in any disease. Detection can be carried out either in tissues or in body fluids, such as ascites, pleural and, most often, in blood serum. The clinical use of tumor markers can be classified into 4 groups: screening and early detection, diagnostic confirmation, prognosis and prognosis of the therapeutic response and monitoring of the disease and relapse. The serum tumor marker level in certain situations can be used in making a diagnosis, predicting the course of a disease, or predicting a response to therapy. Disease monitoring is the most common clinical use of serum tumor markers. A growing tendency to determine the level of tumor markers in blood serum helps to detect a relapse of the disease long before the onset of obvious clinical or radiological signs of the disease. Key words: tumor markers (tumor markers), screening, diagnosis, cancer, antigen, malignancy, laboratory.