Клинико-морфологические особенности хронического тонзиллита у часто болеющих детей разных возрастных групп

Abstract

The aim of the research is to determine the main clinical, morphological and immunohistochemical manifestations of hypertrophy and chronic tonsillitis in different age groups of children who are frequently ill. Materials and methods. The objects of the research were the medical histories and surgical materials after tonsillotomy (patients under the age of 6 inclusive) and tonsillectomy (patients from 7 years old) of 48 children’s tonsils. 4 age groups of children were identified. Qualitative assessment of epithelial cells, subepithelial layer of connective tissue, contents of lacunae, follicular and interfollicular lymphoid tissue, stromal component of palatine tonsils as well as distribution of T- and B-lymphocytes in palatine tonsils’ tissue was performed. Morphological changes in the lymphoid tissue of palatine tonsils in children of patients under the age of 6 indicate the preservation of immune activity during interaction with most foreign invader. The most pronounced decrease in the volume of lymphoid tissue because of fibrosis is observed in children between the ages 13 – 18 years old.