Abstract

A combination of oral Prednisolon and ventilation tube insertion was tried in 5 patients (6 ears) with the primary middle ear cholesterol granuloma manifesting blue eardrums. The patients, aged 6 to 19 years, were given 0.5-4mg/kg of body weight of oral prednisolon tapered over 10 to 14 days, and a ventilation tube was inserted during or immediately after the course of prednisolon. All 6 middle ears have been dry and well ventilated with the ventilation tubes in position with good hearing for 4 to 31 months, and CTs have revealed good aeration of the mastoids. Three courses of this therapy were required to obtain a dry middle ear in 1 of the 6 ears, but only 1 course was necessary in the remaining 5 ears. No serious side effects of this therapy were observed except for transient steroid acne in 1 patient. This combination therapy was considered to be worth trying in the treatment of the middle ear cholesterol granuloma.

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