Abstract
A calculation method formulated on the basis of both the Donnan equilibrium and the Nernst-Planck equation of flux is presented in order to predict ionic transport across charged membranes in multi-component ionic systems. The method enables us to simulate ionic transport against its concentration gradient. The simulations and the experiments revealed that the maximum ion concentration ratio of the bulk phases at either side of the membrane depends on both the membrnae charge density and the ionic mobility in the membrane. Simulations in a model system of hemodialysis lead to new improved dialysis methods for efficient removal of serum phosphate which utilize a positively charged membrane dialyzer and/or polycation dialysate solution. The calculations of ionic transport across a bipolar membrane in multi-component ionic systems show that the ionic transport against its concentration gradient occurs in the direction either of or opposite to the concentration of the driving ions depending on the values of the mobility of the driving ions and the charge density and thickness of the negative and positive components of the membrane. The permselectivity of the membrane for ionic valence depends on the bipolar direction.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
