Abstract
The stomach and duodenum of 76 patients with abnormal sensations in the throat were examined by esophagogastroduodenal panendoscopy, and the results were compared with those of 91 patients with abdominal complaints. Of the 76 patients,10 patients (13.0%)had severe gastric or duodenal disease (gastric ulcer, duodenal ulcer or verrucous gastritis),35 patients (46.0%) had slight disease (erosive gastritis, duodenitis or gastric duodenal ulcer scar), and 29 pateints (38.0%) were normal.Antiulcer drugs were significa n tly effective in alleviating the abnormal sensation in the throat in patients with severe gastric or duodenal disease, but had only a placebo effect in patients with slight disease. An abnormal sensation in the throat may be induced by hyperconstriction of the cervical muscles through central reflex of the vagus nerve, which is stimulated by gastroduodenal disease.
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