Abstract
A case of a 84-year-old man with malignant schwannoma of the right sole and the right thigh was reported. There was no family history of von Recklinghausen's disease. The tumor of the right sole had been excised twice during past two years before he visited our hospital. The reccurent tumors were firm, flesh-colored nodules of the right sole and a subcutaneuos nodule of the right thigh.These tumors were predominantly composed of epithelioid cells with some spindle cell area. Some neoplastic cells had wavy, buckled nuclei. No abnormal mitotic figures were observed. There was no evidence of origin from the peripheral nerve. The neoplastic cells were positive for S-100 protein and negative for desmin.
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