Прижизненная микроциркуляция сосудов брыжейки крыс до и после воздействия локального отрицательного давления

Abstract

Introduction. Microcirculatory disorders are the cornerstone of a large number of diseases, therefore during the treatment restoration of functions of microvessels using various ways is necessary. Nowadays, the research of non invasive, physiotherapeutic and effective methods of influence is being actual. Materials and methods. Observation of vital microcirculation under the influence of a local abdominal decompression was made on a mesentery of rats. Changes of length of mesentery vessels and width of their gleam was registered and estimated with curvimeter. Results and discussions. Established that sessions of a local abdominal decompression increase in number of open vessels in mesentery, and also to increase in width of a gleam of microvessels: right after LNP (local negative pressure) session length of microvessels of mesentery was increased twice, in 30 minutes after the session of LNP length of microvessels was increased by 1,6 times, in 2 hours - by 1,5 times. Width of gleam of mesentery vessels also changed during and after LNP: right after LOD session width of vascular gleams was increased by 2,3 times, after 30 minutes - by 1,9 times, after 2 hours - by 1,8 times. Conclusion. Local negative pressure influence upon abdominal area is an effective and physiologic method of toxins removal from an organism, decreasing the severity of intoxication. The method can be applied both independently and in a complex with other medical actions.