Abstract
In patients with blood diseases, maintaining a proper ward environment as regards temperature and humidity and effective drug treatment are important in preventing the development of deep mycosis. We investigated the influences of temperature and humidity and use of antifungal agents on the incidence of pulmonary aspergillosis in such patients. The subjects were 132 patients admitted to our hematology ward between January 1999 and December 2004. Of the 132 patients, 22 developed pulmonary aspergillosis but 110 did not. There were no significant differences in patient background between these patients. The incidence of pulmonary aspergillosis was high (observed significance level of test : 0.004) during summer when the mean humidity in the ward was high. Administration of the antifungal agent micafungin for prevention or treatment reduced incidence (observed significance level of test : 0.042). Based on these findings, we conclude that proper control of ward humidity and selection of an effective antifungal agent are important factors in reducing the incidence of aspergillosis in wards where patients are being treated for blood diseases.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
