АУТОТРАНСПЛАНТАЦИЯ КРИОКОНСЕРВИРОВАННОЙ ОВАРИАЛЬНОЙ ТКАНИ - НОВЫЙ МЕТОД СОХРАНЕНИЯ ФЕРТИЛЬНОСТИ У ПАЦИЕНТОК С ЛИМФОМАМИ

Abstract

Treatment of lymphomas has considerably improved survival rates for young women. As a result women’s reproductive function will be damaged due to the gonadotoxicity of chemo- and radiotherapy regimens. Fertility preservation using cryopreservation of ovarian tissue is appropriate for women receiving chemotherapy and radiotherapy for treatment of lymphomas. Progress in assisted reproduction techniques and ongoing rapidly developing research protocols during last years have made possible to offer not only established but also experimental fertility preservation options to young women with Hodgkin’s and Non-Hodgkin’s lymphomas facing gonadal failure. Before patients will be submitted to oncological treatment, the right ovarian cortex is extracted by robotic surgery and then cryopreserved according to standard procedure. As soon as the patient is free of disease, the right ovarian cortex will be thawed and implanted onto the left ovarian medulla using robotic surgery. Ovarian tissue autotransplantation is feasible option to preserve ovarian function and further fertility in young women at risk of developing premature ovarian failure due to chemotherapy and/or radiotherapy. Gynecologists, oncologists and reproductive professionals should be aware that ovarian tissue autotransplantation may be considered and reproductive function can be preserved in any case when fertility might be threatened.