Abstract
Chiralscreen® is biocatalyst, i.e. enzyme for asymmetric synthesis. Chiralscreen® OH for chiral alcohols and Chiralscreen® NH for chiral amino acids and amines are available. It catalyzes the desired reaction in high regio/stereo selectivity under mild conditions without dangerous reagents. For example, chemical reduction requires hydride reagent or hydrogen, however, pseudo-hydride donor of reduction with Chiralscreen® is formate or glucose. The solvent is water, and the reactions proceeds under ambient pressure and room temperature. Therefore, special facilities and safety counterplans are not needed for the reactions. The solubility of substrate in the water is not essential for the reaction. We have an example that slightly soluble ketone (solubility in water is 0.05%) is reduced quantitatively in perfect selectivity. Chiralscreen® is produced using recombinant cell, however, endotoxin, DNA, and/or proteins derived from microbe are not detected in the product.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
