Προσδιορισμός με αναλυτικές μεθόδους ουσιών που διεγείρουν το Κεντρικό Νευρικό Σύστημα

Abstract

The purpose of this thesis is to introduce its readers to the substances that have a stimulating effect on the CNS, and are characterized as psychostimulants, with particular emphasis on caffeine, theophylline and theobromine. Important points, before listing the methods used to determine them, are the knowledge and understanding of the metabolism of substances, as well as their mechanism of action. In general, these substances act in different systems and therefore reference is made to their individual effects on the CNS. A variety of methods, timeless and modern newly introduced, are used for the qualitative and quantitative determination of methylxanthines in various types of tea, soft drinks, coffee beans and even blood plasma. Several methods use similar procedures to prepare the sample, however the course of the analysis may differ. Advantages and disadvantages govern each method, therefore the choice and use of a method depends on many parameters. The aim of this thesis is to make known as many methods as possible for the simultaneous or partial determination of caffeine, theophylline and theobromine. More information about each method is provided in the individual chapters.