ブラッシング後のヒト歯肉ヘモグロビン量と酸素飽和度の変化 健常歯肉と炎症歯肉の比較

Abstract

The purpose of this study was to evaluate the effect of tooth brushing on hemoglobin concentration and oxygen saturation in clinically healthy gingivae and inflamed gingivae of humans. Thirteen subjects with healthy gingivae and ten subjects with inflamed gingivae participated in this study. Hemoglobin concentration (Hb index) and oxygen saturation (SO2 index) in papillary gingivae were assessed using a noninvasive tissue reflectance spectrophotometer. Measurements were made before and continuously after brushing in a standardized manner. In healthy gingivae, the Hb index increased 30-40% and then decreased 10-20% from baseline within the first 5min after the release of pressure from brushing. The SO2 index increased significantly between 1min and 30min after brushing. The Hb index and the SO2 index returned to baseline within 60min and 90min after brushing, respectively. In inflamed gingivae., changes in the Hb index and the SO2 index showd patterns similar to those in healthy gingivae. However, the Hb index reached minimum level at 10min after brushing and did not recover during the monitoring period. A significant increase in SO2 index was observed between 5 and 10min after brushing. In conclusion, tooth brushing caused a rapid increase followed by a decrease in hemoglobin concentration and an increase in oxygen saturation in human gingivae, and these microvascular responses occurred slowly in inflamed gingivae.