ВЛИЯНИЕ ИНТЕРМЕДИАТОВ ЦИКЛА КРЕБСА НА РОСТ И РАЗВИТИЕ КУЛЬТУРЫ СИНЕГНОЙНОЙ ПАЛОЧКИ

Abstract

This paper investigates the effect of organic acids - Krebs cycle intermediates (citric, α-Ketoglutaric, succinic, malic and oxalic acids) - taken in concentrations from 10 -9 to 10 -15 M on the growth of pure Pseudomonas aeruginosa, its developmental stages, heredity and multiplication. It is established that ultra-small concentrations of the Krebs cycle intermediates do stimulate the growth of P. aeruginosa. Nanopreparations based on the Krebs cycle acids with their concentrations ranging from 10 -9 to 10 -12 M are shown to exhibit the highest growth-stimulating action. In an experiment aimed at investigating a joint action of Krebs cycle intermediate nanopreparations and herbicides, a synergistic effect of increased herbicide phytotoxicity was revealed. The propensity of the P. aeruginosa strain to accelerated reproduction under the influence of a stimulating agent is not preserved in its third generation. It is determined that the stimulation of P. aeruginosa growth has limit values for each concentration and is of a cyclical character. A nanopreparation with a concentration of 10 -11 M is shown to exhibit the highest stimulating action.