オリゴ糖をＫｅｙ出発物質とする生理活性物質の合成 Ｆｅｒｒｉｅｒ反応との組み合わせを中心に

Abstract

The readily available di- and tri-saccharides such as maltose and maltotriose were employed as the starting materials or building blocks to prepare biologically active pseudooligosaccharides. These attempts involving an advantageous utilization of the internal glycosidic linkages of the starting oligosaccharides were fulfilled on the basis of the methodology developed for their regioselective protection. All chiral carbocyclic constituents of the target compounds were prepared by applying the Ferrier's carbocyclization reaction to the corresponding carbohydrate precursors.