Abstract
This research includes the preparation of series of chalcone compounds using the Claisen – Schmidt method between Cyclohexane and a group of different aromatic aldehydes (2-Chlorobenzaldehyde) and (3-Nitrobenzaldehyde), (4-Methoxybenzaldehyde), (Vanillin), (4- Chlorobenzaldehyde), and (N,N- 4-Dimethylaminobenzaldehyde). In the second step, the chalcones were converted to pyrazoline compounds by reacting with hydrazine hydrate and with the presence of glacial acetic acid, and pyrazoline compounds containing the acetyl group which were utilized by their interaction with different aromatic benzaldehydes to obtain new alpha-beta unsaturated compounds, prepared in the acidic medium. And the last step ,a number of disproportionate and effective aromatic compounds were prepared with the expected vital efficacy by the reaction of the chalcones from the last step with hydrogen peroxide to give triple-oxirane compound (34-31) and reaction with hydrazine hydrate in the presence of glacial acetic acid to prepare pyrazoline compounds (30-27) and reaction with urea to give hexagonal pyrimidine compounds (34-31). The compounds prepared with the available physical and spectral methods were diagnosed, so the infrared spectrum, Nuclear magnetic resonance spectroscopy, melting point measurement, and color changes were measured.
Highlights
والجالكؾنات مخكبات لا تحوب بالساء وتحوب في معغؼ السحيبات العزؾية وتدتخجم كسادة اولية لمعجيج مؽ التفاعلات السيسة في البشاء العزؾي ( ،)2وليا استخجامات عمى الرعيجيؽ الظبي والرشاعي(.)3
This research includes the preparation of series of chalcone compounds using the Claisen – Schmidt method between Cyclohexane and a group of different aromatic aldehydes (2Chlorobenzaldehyde) and (3-Nitrobenzaldehyde), (4Methoxybenzaldehyde), (Vanillin), (4- Chlorobenzaldehyde), and (N,N- 4-Dimethylaminobenzaldehyde)
The chalcones were converted to pyrazoline compounds by reacting with hydrazine hydrate and with the presence of glacial acetic acid, and pyrazoline compounds containing the acetyl group which were utilized by their interaction with different aromatic benzaldehydes to obtain new alpha-beta unsaturated compounds, prepared in the acidic medium
Summary
والجالكؾنات مخكبات لا تحوب بالساء وتحوب في معغؼ السحيبات العزؾية وتدتخجم كسادة اولية لمعجيج مؽ التفاعلات السيسة في البشاء العزؾي ( ،)2وليا استخجامات عمى الرعيجيؽ الظبي والرشاعي(.)3. الفيديائية في ججول رقؼ (.)2 -3تحزير الجالكهنات السذتقة من مركبات الباي ارزولين في الهسط الحامزي)-: (12)(13 عشج مدج ( )0.001molمؽ مخكبات الباي اخزوليؽ السحابة في الايثانؾل السظمق مع ( )3-4قظ اخت مؽ حامض الخميػ الثمجي ( )0.001molمؽ الالجيييجات الاروماتية السختمفة ويرعج السديج لسجة( 3ساعات) ،بعج انتياء التفاعل يخكد السحمؾل الى الشرف ويبخد ،يجسع ال اخسب الستكؾن وتعاد بمؾرتو بالإيثانؾل .
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