Abstract
Two cases of benign lymphoepithelial lesions (BLEL) are reported along with a discussion on the expression of cytokeratin.Case 1: A 46-year-old man was referred to our clinic with a chief complaint of swelling at the right submandibular gland. Computed tomography showed the submandibular gland as a homogeneous high density area. Gallium scintigraphy demonstrated a clear hot spot at the same region. The submandibular mass was extirpated extraorally. Pathologically, there were atrophic changes of the ducts and acini, acompanied by severe lymphoid cell infiltration.Case 2: A 55-year-old man complained of swelling of the right buccal region. Magnetic resonance imaging revealed a homogeneous mass showing low intensity in T1 weighted SE and slightly high intensity in T2 weighted SE at the right lower parotid region. Examination of a specimen of the extraorally excised mass showed severe lymphoid tissue infiltration interspersed with myoepithelial islands in the atrophic parotid gland.Immunohistochemical staining was performed to check for the expression of the cytokeratin in the atrophic salivary gland. All duct-like structures (DLSs) reacted positively against K8.13 and cytokeratin #7 and #18. On the other hand, # 8 was negative especially in small DLSs.
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