Клинические особенности, качество жизни и прогноз больных с хроническим кардиоренальным синдромом

Abstract

AIM. The aim of this study was to investigate clinical features, quality of life and prognosis in patients with chronic heart failure (CHF) and patients with CHF associated with chronic kidney disease (CKD). PATIENTS AND METHODS. 203 patients with CHF (130 males and 73 females, mean age was 61,8±9,6 years) were examined. CHF was defined according to the Russian guidelines for the diagnosis and treatment of chronic heart failure, 2012. CKD was defined according to the Russian guidelines for the diagnosis, prevention and treatment of CKD, 2012.Patients with CHF and CKD with GFR <60 mL/min/1,73 m2were included in group of chronic cardiorenal syndrome (CRS). Charlson comorbidity index, duration of hospitalization for a year follow up, clinical and psychological characteristics and quality of life in patients with CHF were estimated. RESULTS. 89 (44%) patients had chronic kidney disease (CKD) with glomerular filtration rate<60mL/min/1,73 m2 (chronic cardiorenal syndrome). Рatients with chronic cardiorenal syndrome had a higher comorbidity. Patients with CRS were hospitalized due to exacerbation CHF for year more often thanpatients without CRS. Рatients with chronic cardiorenal syndrome had expressed emotional discomfort, the presence of depressive, disadaptive trends, decreased of quality of life, both in the physical and the psychological aspects. CONCLUSION. Chronic kidney disease have a negative impact both on the clinical course and quality of life, psychological status and prognosis of patients with CHF. At the same time, patients with CRS have a high comorbidity, they are characterized by the presence of hypochondria and depression and low quality of life, which should be taken into account in the diagnosis and treatment of this group and assessment of prognosis.