ПРИНЦИПЫ ПРОФИЛАКТИРОВАНИЯ АНТИБИОТИКОРЕЗИСТЕНТНОСТИ ПРИ ЛЕЧЕНИИ УРОЛОГИЧЕСКОГО СИНДРОМА КОШЕК

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The article presents data on the occurrence of urological syndrome in cats of different age and gender groups and the structure of diseases of the lower urinary tract, leading to its development. The most frequently detected pathology was idiopathic feline cystitis (IFC) 82.3 %, urocystolithiasis and bacterial cystitis were less frequently detected – 10.3 % and 7.4 %, respectively. In the differential diagnosis of recurrent cystitis by bacteriological seeding of urine, it was found that more often the cause of the resumption of dysuria was IFC – 73.7 % of negative urine seeding. In other cases, the bacterial etiology of bladder inflammation was confirmed and uropathogens were identified: E. faecalis, E. faecium – 10.5 %, P. mirabilis – 5.3 % of results. When diagnosing cystitis in cats, the following algorithm should be followed: the primary instrumental diagnostic method is ultrasound (the fact of cystitis is established: thickening of the bladder wall, changes in its structure, the presence of suspension and / or concretions in the organ cavity), to differentiate the etiology of cystitis, it is necessary to use laboratory diagnostic methods – general analysis and bacteriological urine culture. Drug treatment consisted of anesthesia (idiopathic cystitis), and in case of septic cystitis, etiotropic therapy was additionally prescribed. Analgesia was carried out in a complex with the use of drugs from the group of nonsteroidal anti-inflammatory drugs (NSAIDs) – meloxicam 0.05 mg/kg 1 time per day and alpha-blockers – terazosin as an antispasmodic at a dose of 0.5 mg /cat 2 times a day. Antibacterial therapy was used strictly according to the results of bacteriological urine culture: the first–line drug of choice was used – amoxicillin with clavulanic acid, reserve antibiotics – cefixime, marbofloxacin; dosages, frequency of administration per day, the course of treatment was prescribed to each patient individually, according to the diagnostic results. The algorithm of actions of a veterinarian when working with cystitis in cats, developed during this study, will help to avoid uncontrolled use of antibiotics, and, as a consequence, the development of antibiotic resistance