Abstract
Changes in euglobulin lysis time (ELT) and Bβ15-42 peptide were investigated on 14 patients with benign disease and 24 with malignant disease before and after operation. ELT prolonged significantly in patients with malignant disease compared to one with benign disease on the first and second postoperative day.A significant increase of Bβ15-42 peptide was found in patients with malignant disease compared to patients with benign disease, though a definite increase was found in the latter group compared to healthy control. No significant difference in Bβ15-42 peptide was found between both patient groups postoperatively, though it increased with linear pattern.The same investigation was performed on patient who had intermittent compression of the legs for 48 hours postoperatively. Shortning of ELT was found in them compared to control. No significant difference in Bβ15-42 peptide was found between both groups, though it increased with linear pattern in both postoperatively. It suggests that no influence on activity of plasmin was produced by leg compression.
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