Ефективність комплексного лікування при асоціативному перебігу дерматитів у собак

Abstract

Currently, skin pathology in dogs is often recorded and is approximately 32,5-55,2 %. Associated dermatitis in dogs has a multicomponent structure of the etiological factors associated with active action on the skin of acaro-fungal agents. Clinical manifestation of the disease is characterized by the presence of significant areas of alopecia, lichenization, vesicles, pustules, erosions, ulcers, scabs on the skin in the areas of the muzzle, ears, petioles of the extremities, severe skin itching and prolonged treatment and remission. The purpose of the work is to develop a modern strategy for the treatment of associative dermatitis in dogs caused by the causative agent of demodicosis and trichophytes. The research was carried out on dogs with skin diseases that belonged to the inhabitants of Kharkiv during the period 2018-2019. At the first stage of the research, anamnestic data was collected, taking into account age, breed, conditions of keeping animals, the type of diet, planned antiparasitic treatments. The second stage of the study included general clinical studies and special diagnostic criteria (parasitological and mycological tests). According to the results of parasitological and mycological studies, 35.3% have associated associative etiology dermatitis caused by the causative agents of Demodex canis and dermatophytes of the genus Trichophyton mentagrophytes. The disease was most commonly registered in dogs under the age of 7-9 months and 2-6 years old. Acaricidal therapy included the use of the drug Simparika (active ingredient sarolaner (Zoetis, USA) and avertsectinum ointment. Antifungal therapy consisted of the use of the drug Intraconazole and external treatments with Imaverol (active ingredient - enilconazole, ELANCO, Austria). Antibacterial therapy was presented by «Sinulox RTU» (Zoetis, USA) (acting substance amoxicillin and clavulanic acid). To facilitate the penetration of the drug through the skin, pretreatment of animals was performed using the keratolytic zooshampun «VetExpert» (Poland). For the correction of the immune condition, the drug «PDE» - denatured placenta emulsified, Pharmax, Ukraine) was used. For normalization of the liver function, the drug «Gepavikel» (manufacturer KELA (Belgium) was injected). Control over the course of the disease was carried out on the basis of a study of skin scrapers every 3-4 weeks. The scissors were taken from the same sites that were examined prior to treatment, and further investigated new areas with lesions. Treatment was performed for 2 months until 2 negative scratches of the skin were obtained. After recovery, control was performed at 3-month intervals for 1 year.