Abstract
Abstract - The objective of this study was to determine the biological activities of Sorglum bicolor extracts. Organic fractions, including n -Hexane, EtOAc, and n -BuOH fractions were obtained from the methanol extract of Sorglum bicolor M.. In DPPH radical scavenging activity, SC 50 values of methanol extract and EtOAc fraction were exhibited 0.66±0.26 μg/mL and 1.03±0.02 μg/mL, respectively. Contents of total polyphenol and flavonoids in EtOAc fraction, which were much higher than those of other fractions, were 58.12 mg/g and 4.79 mg/g respectively. Also, effects of reducing power was strongly showed in EtOAc fraction. α-Glucosidase and α-amlyase inhibition activities were showed the higher effect in D.W. fraction (2.83 μg/mL, 36.64 μg/mL). In MTT assay in the AGS, HT29 and HCT116 cell lines were significantly higher in the n -BuOH fraction than in the other fractions at 50 μg/mL concentration of extracts. Key words - Antioxidant, Total flavonoid contents, Total polyphenol contents, MTT assay, DPPH assay, AGS, HT29, HCT116
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
